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Article

Study of cholesterol metabolism in Huntington's disease.

Biochemical and biophysical research communications - 11 Apr 2014

Leoni Valerio, Caccia Claudio

Abstract excerpt

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by an abnormal expansion of a CAG repeat in the huntingtin gene. Neurodegeneration of striatum and cortex with a severe atrophy at MRI are common findings in HD. The expression of genes involved in the cholesterol biosynthetic pathway such as HMG-CoA reductase and the levels of cholesterol, lanosterol, lathosterol and...

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Identifiers

PMID: 24525128
DOI: 10.1016/j.bbrc.2014.01.188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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