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Article

The acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis.

American journal of physiology. Gastrointestinal and liver physiology - 1 Apr 2014

Turgeon Naomie, Gagné Julie Moore, Blais Mylène, Gendron Fernand-Pierre, Boudreau François, Asselin Claude

Abstract excerpt

Histone deacetylases (Hdac) remove acetyl groups from proteins, influencing global and specific gene expression. Hdacs control inflammation, as shown by Hdac inhibitor-dependent protection from dextran sulfate sodium (DSS)-induced murine colitis. Although tissue-specific Hdac knockouts show redun...

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Source

Identifiers

PMID: 24525021
DOI: 10.1152/ajpgi.00393.2013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24525021-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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