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Article

Function of Histone Deacetylase Inhibitors in Inflammation

1 Jan 2011

Abstract excerpt

Histone deacetylases (HDACs) display multi-faceted roles in coordinating the interaction of intracellular signaling pathways with chromatin remodeling and transcription factor function to finely specify gene alterations and maintenance of gene expression during cellular activation, proliferation, and differentiation. These processes, epigenetic and non-epigenetic, are critical to the development of both the...

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PMID: 21740352
DOI: 10.1615/critrevimmunol.v31.i3.40

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