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Article

ER sheet persistence is coupled to myosin 1c-regulated dynamic actin filament arrays.

Molecular biology of the cell - 1 Apr 2014

Joensuu Merja, Belevich Ilya, Rämö Olli, Nevzorov Ilya, Vihinen Helena, Puhka Maija, Witkos Tomasz M, Lowe Martin, Vartiainen Maria K, Jokitalo Eija

Abstract excerpt

The endoplasmic reticulum (ER) comprises a dynamic three-dimensional (3D) network with diverse structural and functional domains. Proper ER operation requires an intricate balance within and between dynamics, morphology, and functions, but how these processes are coupled in cells has been unclear. Using live-cell imaging and 3D electron microscopy, we identify a specific subset of actin filaments localizing to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24523293
DOI: 10.1091/mbc.E13-12-0712
PMCID: PMC3967974

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