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Article

Fluctuation of Rac1 activity is associated with the phenotypic and transcriptional heterogeneity of glioma cells.

Journal of cell science - 15 Apr 2014

Yukinaga Hiroko, Shionyu Clara, Hirata Eishu, Ui-Tei Kumiko, Nagashima Takeshi, Kondo Shinji, Okada-Hatakeyama Mariko, Naoki Honda, Matsuda Michiyuki

Abstract excerpt

Phenotypic heterogeneity of cancer cells is caused not only by genetic and epigenetic alterations but also by stochastic variation of intracellular signaling molecules. Using cells that stably express Förster resonance energy transfer (FRET) biosensors, we show here a correlation between a tempor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24522191
DOI: 10.1242/jcs.139733

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24522191-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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