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Article

Caenorhabditis elegans nicotinic acetylcholine receptors are required for nociception.

Molecular and cellular neurosciences - 1 Mar 2014

Cohen Emiliano, Chatzigeorgiou Marios, Husson Steven J, Steuer-Costa Wagner, Gottschalk Alexander, Schafer William R, Treinin Millet

Abstract excerpt

Polymodal nociceptors sense and integrate information on injurious mechanical, thermal, and chemical stimuli. Chemical signals either activate nociceptors or modulate their responses to other stimuli. One chemical known to activate or modulate responses of nociceptors is acetylcholine (ACh). Across evolution nociceptors express subunits of the nicotinic acetylcholine receptor (nAChR) family, a family of ACh-gated...

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Identifiers

PMID: 24518198
DOI: 10.1016/j.mcn.2014.02.001
PMCID: PMC4258610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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