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Article

Impact of heterozygote CFTR mutations in COPD patients with chronic bronchitis.

Respiratory research - 11 Feb 2014

Raju S Vamsee, Tate Jody H, Peacock Sandra K G, Fang Ping, Oster Robert A, Dransfield Mark T, Rowe Steven M

Abstract excerpt

BACKGROUND: Cigarette smoking causes Chronic Obstructive Pulmonary Disease (COPD), the 3rd leading cause of death in the U.S. CFTR ion transport dysfunction has been implicated in COPD pathogenesis, and is associated with chronic bronchitis. However, susceptibility to smoke induced lung injury is...

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Source

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Identifiers

PMID: 24517344
DOI: 10.1186/1465-9921-15-18
PMCID: PMC3925354

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24517344-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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