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Article

Asthma and COPD in cystic fibrosis intron-8 5T carriers. A population-based study.

Respiratory research - 9 Oct 2005

Dahl Morten, Tybjaerg-Hansen Anne, Lange Peter, Nordestgaard Børge G

Abstract excerpt

BACKGROUND: Carriers of cystic fibrosis intron-8 5T alleles with high exon-9 skipping could have increased annual lung function decline and increased risk for asthma or chronic obstructive pulmonary disease (COPD). METHODS: We genotyped 9131 individuals from the adult Danish population for cystic fibrosis 5T, 7T, 9T, and F508del alleles, and examined associations between 11 different genotype combinations, and...

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Identifiers

PMID: 16212675
DOI: 10.1186/1465-9921-6-113
PMCID: PMC1277850

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