CFTR Heterozygotes Are at Increased Risk of Respiratory Infections: A Population-Based Study

Abstract excerpt

Abstract Background Patients heterozygous for mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene may be more susceptible to respiratory infections than the general population. Methods. We conducted a retrospective case–control study using health insurance claims. We identified patients as either highly likely to be CFTR heterozygotes (CF carriers diagnosed during genetic counseling,...

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