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Article

Tissue factor residues that putatively interact with membrane phospholipids.

PloS one - 1 Jan 2014

Ke Ke, Yuan Jian, Morrissey James H

Abstract excerpt

Blood clotting is initiated by the two-subunit enzyme consisting of the plasma protease, factor VIIa (the catalytic subunit), bound to the integral membrane protein, tissue factor (the regulatory subunit). Molecular dynamics simulations have predicted that certain residues in the tissue factor ectodomain interact with phosphatidylserine headgroups to ensure optimal positioning of the tissue factor/factor VIIa...

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Identifiers

PMID: 24516673
DOI: 10.1371/journal.pone.0088675
PMCID: PMC3916442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Tissue factor residues that putatively interact with membrane phospholipids.PMID 24516673Read ↗

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