Article
A framework including recombination for analyzing the dynamics of within-host HIV genetic diversity.
PloS one - 1 Jan 2014
Sargsyan Ori
Abstract excerpt
This paper presents a novel population genetic model and a computationally and statistically tractable framework for analyzing within-host HIV diversity based on serial samples of HIV DNA sequences. This model considers within-host HIV evolution during the chronic phase of infection and assumes that the HIV population is homogeneous at the beginning, corresponding to the time of seroconversion, and evolves...
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