Article
Familial clustering in Italian progressive-onset and bout-onset multiple sclerosis.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 May 2014
Guaschino Clara, Esposito Federica, Liberatore Giuseppe, Colombo Bruno, Annovazzi Pietro, D'Amico Emanuele, Cavalla Paola, Capello Elisabetta, Capra Ruggero, Galimberti Daniela, Tedeschi Gioacchino, Grimaldi Luigi, Leone Maurizio, D'Alfonso Sandra, Martinelli Vittorio, Comi Giancarlo, Martinelli-Boneschi Filippo
Abstract excerpt
Multiple sclerosis (MS) is a complex disease triggered by environmental and genetic agents, and clinically characterized by bout onset (BOMS) or progressive onset (PrMS). We collected clinical and familial aggregation data in a cohort of 518 Italian PrMS patients, and compared with 400 BOMS cases...
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