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Article

Aggregation of multiple sclerosis genetic risk variants in multiple and single case families.

Annals of neurology - 1 Jan 2011

Gourraud Pierre-Antoine, McElroy Joseph P, Caillier Stacy J, Johnson Britt A, Santaniello Adam, Hauser Stephen L, Oksenberg Jorge R

Abstract excerpt

OBJECTIVE: Multiple sclerosis (MS) is a multifactorial neurologic disease characterized by modest but tractable heritability. Genome-wide association studies have identified and/or validated multiple polymorphisms in approximately 16 genes associated with susceptibility. We aimed at investigating the aggregation of genetic MS risk markers in individuals by comparing multiple- and single-case families. METHODS: A...

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Identifiers

PMID: 21280076
DOI: 10.1002/ana.22323
PMCID: PMC3511846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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