Article
Involvement of the iNKT cell pathway is associated with early-onset eosinophilic esophagitis and response to allergen avoidance therapy.
The American journal of gastroenterology - 1 May 2014
Lexmond Willem S, Neves Joana F, Nurko Samuel, Olszak Torsten, Exley Mark A, Blumberg Richard S, Fiebiger Edda
Abstract excerpt
OBJECTIVES: Recent experimental evidence suggests that environmental microbial factors early in life determine susceptibility to allergic diseases through inappropriate chemotaxis and local activation of CD1d-restricted, invariant chain natural killer T (iNKT) cells. In this study, we analyzed the involvement of these pathways in pediatric patients with eosinophilic esophagitis (EoE) before and after dietary...
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