Article
Invariant natural killer T cells in children with eosinophilic esophagitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jan 2014
Jyonouchi S, Smith C L, Saretta F, Abraham V, Ruymann K R, Modayur-Chandramouleeswaran P, Wang M-L, Spergel J M, Cianferoni A
Abstract excerpt
BACKGROUND: Eosinophilic esophagitis (EoE) is an atopic disease characterized by eosinophilic inflammation in which dietary antigens (in particular, milk) play a major role. EoE is most likely a mixed IgE and non-IgE food-mediated reaction in which overexpression of Th2 cytokines, particularly IL-13, play a major role; however, the cells responsible for IL-13 overexpression remain elusive. Th2-cytokines are...
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