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Article

Detection and monitoring of localized matrix metalloproteinase upregulation in a murine model of asthma

8 Feb 2014

Abstract excerpt

Extracellular proteases including matrix metalloproteinases (MMPs) are speculated to play a significant role in chronic lung diseases, such as asthma. Although increased protease expression has been correlated with lung pathogenesis, the relationship between localized enzyme activity and disease progression remains poorly understood. We report the application of MMP-2/9 activatable cell-penetrating peptides...

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PMID: 24508733
DOI: 10.1152/ajplung.00371.2013

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