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Article

Long-Term Effects of Maternal Diabetes on Blood Pressure and Renal Function in Rat Male Offspring

5 Feb 2014

Abstract excerpt

AIMS/HYPOTHESIS: Gestational diabetes mellitus (GDM) is increasing rapidly worldwide. Previous animal models were established to study consequences of offspring after exposure to severe intrauterine hyperglycemia. In this study we are aiming to characterize the blood pressure levels and renal function of male offspring obtained from diabetic mothers with moderate hyperglycemia. METHODS: We established a rat model...

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PMID: 24505458
DOI: 10.1371/journal.pone.0088269

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