Article
Influence of topography of an endovascular stent material on smooth muscle cell response.
Annals of vascular surgery - 1 Jul 2011
Taneja Vipul, Vertegel Alexey, Langan Eugene M, Laberge Martine
Abstract excerpt
The phenotypic shift of smooth muscle cells (SMCs) from contractile to synthetic phenotype after endovascular stenting has been deemed to be the predominant cause of restenosis. Although substrate topography has been shown to affect SMC response for a variety of polymers, effect of topography on phenotype of SMCs has not been well studied for endovascular stent materials. Thus, the objective of the present study...
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