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Article

DJ-1 upregulates breast cancer cell invasion by repressing KLF17 expression

6 Feb 2014

Abstract excerpt

BACKGROUND: DJ-1 (PARK7) was reported as an oncogene in a Ras-dependent manner. Recent studies have shown that DJ-1 stimulates cell proliferation, cell invasion, and cancer metastasis. However, the molecular mehchanism by which DJ-1 induces cancer cell invasion and metastasis remains unclear. METHODS: Breast cancer cells were transfected with DJ-1 siRNA or DJ-1 overexpression to investigate the effect of DJ-1 on...

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PMID: 24504364
DOI: 10.1038/bjc.2014.40

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