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Article

Id‐1 promotes proliferation of p53‐deficient esophageal cancer cells

27 Feb 2006

Abstract excerpt

The helix-loop-helix protein inhibitor of differentiation and DNA binding (Id-1) is known to promote cellular proliferation in several types of human cancer. Although it has been reported that Id-1 is over-expressed in esophageal squamous cell carcinoma (ESCC), its function and signaling pathways in esophageal cancer are unknown. In our study, we investigated the direct effects of Id-1 on esophageal cancer cell...

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PMID: 16506209
DOI: 10.1002/ijc.21874

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