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Article

Oncogenic Ras/ERK signaling activates CDCP1 to promote tumor invasion and metastasis.

Molecular cancer research : MCR - 1 Oct 2014

Uekita Takamasa, Fujii Satoko, Miyazawa Yuri, Iwakawa Reika, Narisawa-Saito Mako, Nakashima Katsuhiko, Tsuta Koji, Tsuda Hitoshi, Kiyono Tohru, Yokota Jun, Sakai Ryuichi

Abstract excerpt

UNLABELLED: Involvement of Ras in cancer initiation is known, but recent evidence indicates a role in cancer progression, including metastasis and invasion; however, the mechanism is still unknown. In this study, it was determined that human lung cancer cells with Ras mutations, among other popular mutations, showed significantly higher expression of CUB domain-containing protein 1 (CDCP1) than those without....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to MAP Kinase Signaling System

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Source

Identifiers

PMID: 24939643
DOI: 10.1158/1541-7786.MCR-13-0587

Genes

CDCP1
MMP2
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Oncogenic Ras/ERK signaling activates CDCP1 to promote tumor invasion and metastasis.PMID 24939643Read ↗

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