Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ST3GAL1 Promotes Malignant Phenotypes in Intrahepatic Cholangiocarcinoma.

Molecular & cellular proteomics : MCP - 1 Sept 2024

Chen Fanghua, Gao Ke, Li Yan, Li Yin, Wu Yingcheng, Dong Liangqing, Yang Zijian, Shi Jieyi, Guo Kun, Gao Qiang, Lu Haojie, Zhang Shu

Abstract excerpt

Intrahepatic cholangiocarcinoma (iCCA) has a poor prognosis, and elucidation of the molecular mechanisms underlying iCCA malignancy is of great significance. Glycosylation, an important post-translational modification, is closely associated with tumor progression. Altered glycosylation, including aberrant sialylation resulting from abnormal expression of sialyltransferases (STs) and neuraminidases (NEUs), is a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Duct Neoplasms
Share to Cell Movement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholangiocarcinoma

Share to Glycosylation

Share to Neoplasm Invasiveness

Share to NF-kappa B

Share to Proteomics

Share to Sialyltransferases

Source

Open in PubMed Open full text

Identifiers

PMID: 39069074
DOI: 10.1016/j.mcpro.2024.100821
PMCID: PMC11385758

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ST3GAL1 Promotes Malignant Phenotypes in Intrahepatic Cholangiocarcinoma.PMID 39069074Read ↗

Precision N‐glycoproteomics reveals elevated LacdiNAc as a novel signature of intrahepatic cholangiocarcinomaSemantic proximity Read ↗

Integrating Transcriptomics, Glycomics And Glycoproteomics To Characterize Hepatitis B Virus-associated Hepatocellular CarcinomaSemantic proximity Read ↗

Comprehensive analysis of α2,3-sialyltransferases as prognostic biomarkers and immunotherapy targets in kidney renal clear cell carcinomaSemantic proximity Read ↗

LncRNA ST3Gal6‐AS1/ST3Gal6 axis mediates colorectal cancer progression by regulating α‐2,3 sialylation via PI3K/Akt signalingSemantic proximity Read ↗

Terminal fucose mediates progression of human cholangiocarcinoma through EGF/EGFR activation and the Akt/Erk signaling pathwaySemantic proximity Read ↗

Protein glycosylation in cancers and its potential therapeutic applications in neuroblastomaSemantic proximity Read ↗

O-GlcNAcylation mediates metastasis of cholangiocarcinoma through FOXO3 and MAN1A1Semantic proximity Read ↗

High expression of tissue O-linked glycans is associated with a malignant phenotype of cholangiocarcinoma.Semantic proximity Read ↗

Predictive potentials of glycosylation-related genes in glioma prognosis and their correlation with immune infiltrationSemantic proximity Read ↗

Increased expression of the high‑mannose M6N2 and NeuAc3H3N3M3N2F tri‑antennary N‑glycans in cholangiocarcinomaSemantic proximity Read ↗

Molecular Pathogenesis and Regulation of the miR-29-3p-Family: Involvement of ITGA6 and ITGB1 in Intra-Hepatic CholangiocarcinomaSemantic proximity Read ↗

Bioinformatic analysis and in vitro experiments reveal that N-linked glycosylation related genes STT3A, DDOST and TMEM165 participate in the promotion of hepatocellular carcinoma and Its role in immunotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.