Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An MTHFR variant, plasma homocysteine levels and late-onset coronary artery disease in subjects from southern Iran.

Pakistan journal of biological sciences : PJBS - 15 Aug 2013

Saffari Babak, Senemar Sara, Karimi Mehran, Bahari Marzieh, Jooyan Najmeh, Yavarian Majid

Abstract excerpt

There have been many controversial debates on the role of Hyperhomocysteinaemia (HHcy) as an independent risk factor for Coronary Artery Disease (CAD) during recent years. Furthermore, an alanine/valine (Ala/Val) gene polymorphism at 222nd amino acid of 5,10-methylenetetrahydrofolate reductase (MTHFR) has been considered as a factor that could render this enzyme thermolabile and less active which in turn may...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Angiography
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Stenosis

Share to Homocysteine

Share to Hyperhomocysteinemia

Share to Linear Models

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Source

Identifiers

PMID: 24498831
DOI: 10.3923/pjbs.2013.788.795

Genes

CAD
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An MTHFR variant, plasma homocysteine levels and late-onset coronary artery disease in subjects from southern Iran.PMID 24498831Read ↗

Methylenetetrahydrofolate reductase C677T mutation, plasma homocysteine, and folate in subjects from northern Italy with or without angiographically documented severe coronary atherosclerotic disease: evidence for an important genetic-environmental interaction.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene mutation and hyperhomocysteinemia as a risk factor for coronary heart disease in the Indian population.Semantic proximity Read ↗

[MTHFR genetic variability on coronary artery disease development].Semantic proximity Read ↗

MTHFR gene polymorphism, homocysteine and cardiovascular disease.Semantic proximity Read ↗

The 677C-->T mutation in the methylenetetrahydrofolate reductase gene: associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease.Semantic proximity Read ↗

C677T mutation of methylenetetrahydrofolate reductase gene and serum homocysteine levels in Turkish patients with coronary artery disease.Semantic proximity Read ↗

Genetic polymorphism of MTHFR C677T and premature coronary artery disease susceptibility: A meta-analysis.Semantic proximity Read ↗

Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease.Semantic proximity Read ↗

Serum homocysteine, methylenetetrahydrofolate reductase gene polymorphism and cardiovascular disease in heterozygous familial hypercholesterolemia.Semantic proximity Read ↗

The role of methylenetetrahydrofolate reductase C677T gene polymorphism as a risk factor for coronary artery disease: a cross-sectional study in the Sidoarjo Regional General Hospital.Semantic proximity Read ↗

Association of MTHFR C677T (rs1801133) and A1298C (rs1801131) Polymorphisms with Serum Homocysteine, Folate and Vitamin B12 in Patients with Young Coronary Artery DiseaseSemantic proximity Read ↗

Association of polymorphism in the thermolabile 5, 10-methylene tetrahydrofolate reductase gene and hyperhomocysteinemia with coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.