Genetic polymorphism of MTHFR C677T and premature coronary artery disease susceptibility: A meta-analysis.

doi:10.1016/j.gene.2015.03.062

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Article

Genetic polymorphism of MTHFR C677T and premature coronary artery disease susceptibility: A meta-analysis.

Gene - 1 Jul 2015

Hou Xiaowen, Chen Xin, Shi Jingpu

Abstract excerpt

The association between 5, 10-methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and premature coronary artery disease (PCAD) is controversial. To explore a more precise estimation of the association, a meta-analysis was conducted in the present study. The relevant studies were identified by searching PubMed, EMBASE, the Web of Science, Cochrane Collaboration Database, Chinese National Knowledge...

Topics

Adult
Asian People
China
Coronary Artery Disease
Genetic Predisposition to Disease
Homocysteine
Humans
Methylenetetrahydrofolate Reductase (NADPH2)
Middle Aged
Polymorphism, Single Nucleotide
Publication Bias
Young Adult

Source

Open in PubMed

Identifiers

PMID: 25839940
DOI: 10.1016/j.gene.2015.03.062

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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