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Article

BMI-associated alleles do not constitute risk alleles for polycystic ovary syndrome independently of BMI: a case-control study.

PloS one - 1 Jan 2014

Louwers Yvonne V, Rayner Nigel W, Herrera Blanca M, Stolk Lisette, Groves Christopher J, Barber Thomas M, Uitterlinden Andre G, Franks Stephen, Laven Joop S E, McCarthy Mark I

Abstract excerpt

INTRODUCTION: Polycystic Ovary Syndrome (PCOS) has a strong genetic background and the majority of patients with PCOS have elevated BMI levels. The aim of this study was to determine to which extent BMI-increasing alleles contribute to risk of PCOS when contemporaneous BMI is taken into consideration. METHODS: Patients with PCOS and controls were recruited from the United Kingdom (563 cases and 791 controls) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24498077
DOI: 10.1371/journal.pone.0087335
PMCID: PMC3909077

Genes

FTO
BDNF
ETV5
FAIM2
GNPDA2
KCTD15
MTCH2
NEGR1
TMEM18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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