Article
Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome.
Diabetologia - 1 Jul 2008
Barber T M, Bennett A J, Groves C J, Sovio U, Ruokonen A, Martikainen H, Pouta A, Hartikainen A-L, Elliott P, Lindgren C M, Freathy R M, Koch K, Ouwehand W H, Karpe F, Conway G S, Wass J A H, Järvelin M-R, Franks S, McCarthy M I
Abstract excerpt
AIMS/HYPOTHESIS: Variants in the fat-mass and obesity-associated gene (FTO) influence susceptibility to type 2 diabetes via an effect on adiposity/obesity. Given the important role of obesity in the aetiology of both polycystic ovary syndrome (PCOS) and type 2 diabetes mellitus, our aim was to establish whether FTO variants are also implicated in PCOS susceptibility. METHODS: We performed a genetic association...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.