Article
Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS).
BMC medical genetics - 21 Jan 2010
Tan Susanne, Scherag André, Janssen Onno Eilard, Hahn Susanne, Lahner Harald, Dietz Tiina, Scherag Susann, Grallert Harald, Vogel Carla Ivane Ganz, Kimmig Rainer, Illig Thomas, Mann Klaus, Hebebrand Johannes, Hinney Anke
Abstract excerpt
BACKGROUND: The polycystic ovary syndrome (PCOS), a common endocrine disorder in women of child-bearing age, mainly characterised by chronic anovulation and hyperandrogenism, is often associated with insulin resistance (IR) and obesity. Its etiology and the role of IR and obesity in PCOS are not fully understood. We examined the influence of validated genetic variants conferring susceptibility to obesity and/or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.