Article
Candidate genes for obesity-susceptibility show enriched association within a large genome-wide association study for BMI.
Human molecular genetics - 15 Oct 2012
Vimaleswaran Karani S, Tachmazidou Ioanna, Zhao Jing Hua, Hirschhorn Joel N, Dudbridge Frank, Loos Ruth J F
Abstract excerpt
Before the advent of genome-wide association studies (GWASs), hundreds of candidate genes for obesity-susceptibility had been identified through a variety of approaches. We examined whether those obesity candidate genes are enriched for associations with body mass index (BMI) compared with non-candidate genes by using data from a large-scale GWAS. A thorough literature search identified 547 candidate genes for...
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