Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reengineering Redox Sensitive GFP to Measure Mycothiol Redox Potential of Mycobacterium tuberculosis during Infection

30 Jan 2014

Abstract excerpt

Mycobacterium tuberculosis (Mtb) survives under oxidatively hostile environments encountered inside host phagocytes. To protect itself from oxidative stress, Mtb produces millimolar concentrations of mycothiol (MSH), which functions as a major cytoplasmic redox buffer. Here, we introduce a novel system for real-time imaging of mycothiol redox potential (EMSH ) within Mtb cells during infection. We demonstrate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Legionella and Acanthamoeba research
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24497832
DOI: 10.1371/journal.ppat.1003902

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reengineering Redox Sensitive GFP to Measure Mycothiol Redox Potential of Mycobacterium tuberculosis during InfectionPMID 24497832Read ↗

Uncovering the Roles of <i>Mycobacterium tuberculosis melH</i> in Redox and Bioenergetic Homeostasis: Implications for Antitubercular TherapySemantic proximity Read ↗

Systems analysis reveals alternate metabolic states adopted by <i>Mycobacterium tuberculosis</i> across speciesSemantic proximity Read ↗

Mycobacterial Control of Host Mitochondria: Bioenergetic and Metabolic Changes Shaping Cell Fate and Infection OutcomeSemantic proximity Read ↗

Fluorescent Mycobacterium tuberculosis reporters: illuminating host–pathogen interactionsSemantic proximity Read ↗

Mycobacterium tuberculosis reactivates HIV via exosomes mediated resetting of cellular redox potential and bioenergeticsSemantic proximity Read ↗

<i>Mycobacterium tuberculosis</i> diversity and macrophage heterogeneity dictate phagosomal acidificationSemantic proximity Read ↗

Mycobacterial WhiB6 Differentially Regulates ESX-1 and the Dos Regulon to Modulate Granuloma Formation and Virulence in ZebrafishSemantic proximity Read ↗

Phagosomal acidification coordinates a lipid–redox program underlying antibiotic tolerance in Mycobacterium tuberculosisSemantic proximity Read ↗

Direct visualization of bacterial transcripts in the infected lung illuminates spatiotemporal environmental adaptation of <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

The Oxidative Stress Network of Mycobacterium tuberculosis Reveals Coordination between Radical Detoxification Systems.Semantic proximity Read ↗

The role of thioredoxin proteins in <i>Mycobacterium tuberculosis</i> probed by proteome-wide target profilingSemantic proximity Read ↗

Deciphering the Proteomic Landscape of Mycobacterium tuberculosis in Response to Acid and Oxidative StressesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.