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Article

The Oxidative Stress Network of Mycobacterium tuberculosis Reveals Coordination between Radical Detoxification Systems.

Cell host & microbe - 10 Jun 2015

Nambi Subhalaxmi, Long Jarukit E, Mishra Bibhuti B, Baker Richard, Murphy Kenan C, Olive Andrew J, Nguyen Hien P, Shaffer Scott A, Sassetti Christopher M

Abstract excerpt

M. tuberculosis (Mtb) survives a hostile environment within the host that is shaped in part by oxidative stress. The mechanisms used by Mtb to resist these stresses remain ill-defined because the complex combination of oxidants generated by host immunity is difficult to accurately recapitulate in vitro. We performed a genome-wide genetic interaction screen to comprehensively delineate oxidative stress resistance...

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Identifiers

PMID: 26067605
DOI: 10.1016/j.chom.2015.05.008
PMCID: PMC4465913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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