Article
Transcriptional silencing of Arabidopsis endogenes by single-stranded RNAs targeting the promoter region.
Plant & cell physiology - 1 Apr 2014
Deng Shulin, Dai Hongzheng, Arenas Catalina, Wang Huan, Niu Qi-Wen, Chua Nam-Hai
Abstract excerpt
Transcriptional gene silencing (TGS) of transgenes by promoter-related RNAs has been known for more than a decade. However, the effectiveness and efficiency of silencing of endogenes by single-stranded and inverted repeat (IR) RNA/silencers remain unclear. Here, we demonstrated that a single-stranded antisense (AS) silencer targeting the promoter region can efficiently silence four Arabidopsis endogenes, with...
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