Article
IDN2 has a role downstream of siRNA formation in RNA-directed DNA methylation.
Epigenetics - 1 Aug 2012
Finke Andreas, Kuhlmann Markus, Mette Michael Florian
Abstract excerpt
In plants, a particular class of short interfering (si)RNAs can serve as a signal to induce cytosine methylation at homologous genomic regions. If the targeted DNA has promoter function, this RNA-directed DNA methylation (RdDM) can result in transcriptional gene silencing (TGS). RNA-directed transcriptional gene silencing (RdTGS) of transgenes provides a versatile system for the study of epigenetic gene...
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