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Article

Mobile 24 nt small RNAs direct transcriptional gene silencing in the root meristems of Arabidopsis thaliana.

Current biology : CB - 11 Oct 2011

Melnyk Charles W, Molnar Attila, Bassett Andrew, Baulcombe David C

Abstract excerpt

RNA silencing in flowering plants generates a signal that moves between cells and through the phloem [1, 2]. Nucleotide sequence specificity of the signal is conferred by 21, 22, and 24 nucleotide (nt) sRNAs that are generated by Dicer-like (DCL) proteins [3]. In the recipient cells these sRNAs bind to Argonaute (AGO) effectors of silencing and the 21 nt sRNAs mediate posttranscriptional regulation (PTGS) via...

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PMID: 21962713
DOI: 10.1016/j.cub.2011.08.065

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