Article
Tumor necrosis factor (TNF) and lymphotoxin-alpha (LTA) polymorphisms and risk of non-Hodgkin lymphoma in the InterLymph Consortium.
American journal of epidemiology - 1 Feb 2010
Skibola Christine F, Bracci Paige M, Nieters Alexandra, Brooks-Wilson Angela, de Sanjosé Silvia, Hughes Ann Maree, Cerhan James R, Skibola Danica R, Purdue Mark, Kane Eleanor, Lan Qing, Foretova Lenka, Schenk Maryjean, Spinelli John J, Slager Susan L, De Roos Anneclaire J, Smith Martyn T, Roman Eve, Cozen Wendy, Boffetta Paolo, Kricker Anne, Zheng Tongzhang, Lightfoot Tracy, Cocco Pierluigi, Benavente Yolanda, Zhang Yawei, Hartge Patricia, Linet Martha S, Becker Nikolaus, Brennan Paul, Zhang Luoping, Armstrong Bruce, Smith Alex, Shiao Renee, Novak Anne J, Maynadie Marc, Chanock Stephen J, Staines Anthony, Holford Theodore R, Holly Elizabeth A, Rothman Nathaniel, Wang Sophia S
Abstract excerpt
In an International Lymphoma Epidemiology Consortium pooled analysis, polymorphisms in 2 immune-system-related genes, tumor necrosis factor (TNF) and interleukin-10 (IL10), were associated with non-Hodgkin lymphoma (NHL) risk. Here, 8,847 participants were added to previous data (patients diagnosed from 1989 to 2005 in 14 case-control studies; 7,999 cases, 8,452 controls) for testing of polymorphisms in the TNF...
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