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Article

Influence of factor 5 rs6025 and factor 2 rs1799963 mutation on inhibitor development in patients with hemophilia A--an Israeli-German multicenter database study.

Thrombosis research - 1 Apr 2014

Kenet Gili, Bidlingmaier Christoph, Bogdanova Nadja, Ettingshausen Carmen Escuriola, Goldenberg Neil, Gutsche Sven, Halimeh Susan, Holzhauer Susanne, Kurnik Karin, Limperger Verena, Junker Ralf, Nowak-Göttl Ulrike

Abstract excerpt

OBJECTIVE: The present cohort study was performed to investigate the impact of the factor 5 rs6025 [F5] and the factor 2 rs1799963 [F2] mutations on high-titer inhibitor development [HRI] in patients with severe/moderate-severe hemophilia A [HA]. PATIENTS AND METHODS: 216 patients with F8<2% born between 1980 and 2011 were followed after initial HA diagnosis over the first 200 exposure days. The first HA patient...

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PMID: 24485400
DOI: 10.1016/j.thromres.2014.01.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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