Article
BAFF rs9514828 gene polymorphism and the risk of the development of inhibitors in children with severe haemophilia A.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 May 2022
Hodeib Hossam, El Amrousy Doaa, Youssef Amira, Elaskary Eman, Fouda Mohamed H
Abstract excerpt
INTRODUCTION: Haemophilia A (HA) is an x-linked recessive disease due to deficiency of coagulation factor VIII (FVIII). The development of neutralizing antibodies (inhibitors) against infused FVIII is a major concern. B cell activating factor (BAFF) has been implicated in several autoimmune diseases. AIM: We aimed to evaluate the possible association of BAFF rs9514828 gene polymorphism and the risk of the...
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