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Differences in <scp>T</scp>‐cell responses between <i><scp>M</scp>ycobacterium tuberculosis</i> and <i><scp>M</scp>ycobacterium africanum</i>‐infected patients

31 Jan 2014

Abstract excerpt

In The Gambia, Mycobacterium tuberculosis (Mtb) and Mycobacterium africanum (Maf) are major causes of tuberculosis (TB). Maf is more likely to cause TB in immune suppressed individuals, implying differences in virulence. Despite this, few studies have assessed the underlying immunity to the two pathogens in human. In this study, we analyzed T-cell responses from 19 Maf- and 29 Mtb-infected HIV-negative patients...

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PMID: 24481948
DOI: 10.1002/eji.201343956

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