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Article

Polymorphisms in the CLDN1 and CLDN7 genes are related to differentiation and tumor stage in colon carcinoma.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jul 2014

Hahn-Strömberg Victoria, Askari Shlear, Befekadu Rahel, Matthiessen Peter, Karlsson Sune, Nilsson Torbjörn K

Abstract excerpt

Tight junction is composed of transmembrane proteins important for maintaining cell polarity and regulating ion flow. Among these proteins are the tissue-specific claudins, proteins that have recently been suggested as tumor markers for several different types of cancer. An altered claudin expression has been observed in colon, prostatic, ovarian, and breast carcinoma. The aim of this study was to analyze the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24479816
DOI: 10.1111/apm.12211

Genes

CLDN7
CLDN1

Variants

rs9869263
rs4562
rs374400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms in the CLDN1 and CLDN7 genes are related to differentiation and tumor stage in colon carcinoma.PMID 24479816Read ↗

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