Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The link between MHC class I abnormalities of tumors, oncogenes, tumor suppressor genes, and transcription factors.

Journal of immunotoxicology - 1 Oct 2014

Seliger Barbara

Abstract excerpt

MHC class I abnormalities, frequently detected in tumors of distinct origins, are often associated with disease progression and/or poor patient survival. The underlying molecular mechanisms of these defects are either mediated by structural alterations of MHC class I antigens and/or components of the antigen processing machinery (APM) or by their deregulation, which could occur at the transcriptional,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to Gene Expression Regulation, Neoplastic
Share to Genes, Tumor Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Neoplasms

Share to Oncogenes

Share to Tumor Escape

Share to Tumor Microenvironment

Source

Identifiers

PMID: 24479372
DOI: 10.3109/1547691X.2013.875084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The link between MHC class I abnormalities of tumors, oncogenes, tumor suppressor genes, and transcription factors.PMID 24479372Read ↗

Role of genetic variations on MHC class I antigen-processing genes in human cancer and viral-mediated diseases.Semantic proximity Read ↗

MHC Class I Deficiency in Solid Tumors and Therapeutic Strategies to Overcome It.Semantic proximity Read ↗

Analysis of HLA class I alterations in tumors: choosing a strategy based on known patterns of underlying molecular mechanisms.Semantic proximity Read ↗

Impact of disruptions in antigen processing and presentation machinery on sarcomaSemantic proximity Read ↗

Impact of disruptions in antigen processing and presentation machinery on sarcomaSemantic proximity Read ↗

The biological consequences of altered MHC class I expression in tumours.Semantic proximity Read ↗

Assessment of cancer cell‐expressed HLA class I molecules and their immunopathological implicationsSemantic proximity Read ↗

Cancer Immune Evasion Through Loss of MHC Class I Antigen Presentation.Semantic proximity Read ↗

MHC class I chain-related A: Polymorphism, regulation and therapeutic value in cancer.Semantic proximity Read ↗

Individual HLA heterogeneity and its implications for cellular immune evasion in cancer and beyondSemantic proximity Read ↗

Deciphering the role of alternative splicing in neoplastic diseases for immune-oncological therapiesSemantic proximity Read ↗

The HLA crossroad in tumor immunology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.