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Article

Transcriptional Derepression of the <i>ERVWE1</i> Locus following Influenza A Virus Infection

30 Jan 2014

Abstract excerpt

UNLABELLED: Syncytin-1, a fusogenic protein encoded by a human endogenous retrovirus of the W family (HERV-W) element (ERVWE1), is expressed in the syncytiotrophoblast layer of the placenta. This locus is transcriptionally repressed in adult tissues through promoter CpG methylation and suppressive histone modifications. Whereas syncytin-1 appears to be crucial for the development and functioning of the human...

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PMID: 24478419
DOI: 10.1128/jvi.03628-13

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Transcriptional Derepression of the <i>ERVWE1</i> Locus following Influenza A Virus InfectionPMID 24478419Read ↗

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