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Article

Role of HERV-W Syncytin-1 in Placentation and Maintenance of Human Pregnancy

18 Jun 2009

Abstract excerpt

Over half of human genome contains retroelements, including retrotransposons, retroviruses, and other elements. Human endogenous retroviruses (HERVs) comprise about 8% of human genome. The products of 2 of 16 identified genes of HERV-W seem to play a pivotal role in the placentation. These 2 genes are HERV-W env glycoprotein (syncytin-1) and HERV-FRD env glycoprotein (syncytin-2). It has been shown previously...

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PMID: 19407656
DOI: 10.1097/pai.0b013e31819640f9

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