Article
An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis.
Human molecular genetics - 15 Jun 2014
Morris Derek W, Pearson Richard D, Cormican Paul, Kenny Elaine M, O'Dushlaine Colm T, Perreault Louis-Philippe Lemieux, Giannoulatou Eleni, Tropea Daniela, Maher Brion S, Wormley Brandon, Kelleher Eric, Fahey Ciara, Molinos Ines, Bellini Stefania, Pirinen Matti, Strange Amy, Freeman Colin, Thiselton Dawn L, Elves Rachel L, Regan Regina, Ennis Sean, Dinan Timothy G, McDonald Colm, Murphy Kieran C, O'Callaghan Eadbhard, Waddington John L, Walsh Dermot, O'Donovan Michael, Grozeva Detelina, Craddock Nick, Stone Jennifer, Scolnick Ed, Purcell Shaun, Sklar Pamela, Coe Bradley, Eichler Evan E, Ophoff Roel, Buizer Jacobine, Szatkiewicz Jin, Hultman Christina, Sullivan Patrick, Gurling Hugh, Mcquillin Andrew, St Clair David, Rees Elliott, Kirov George, Walters James, Blackwood Douglas, Johnstone Mandy, Donohoe Gary, O'Neill Francis A, Kendler Kenneth S, Gill Michael, Riley Brien P, Spencer Chris C A, Corvin Aiden
Abstract excerpt
Identifying rare, highly penetrant risk mutations may be an important step in dissecting the molecular etiology of schizophrenia. We conducted a gene-based analysis of large (>100 kb), rare copy-number variants (CNVs) in the Wellcome Trust Case Control Consortium 2 (WTCCC2) schizophrenia sample o...
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