Article
A novel microduplication in INPP5A segregates with schizophrenia spectrum disorder in the family of a patient with both childhood onset schizophrenia and autism spectrum disorder.
American journal of medical genetics. Part A - 1 Jun 2021
Fernandez Arnaud, Drozd Małgorzata, Thümmler Susanne, Bardoni Barbara, Askenazy Florence, Capovilla Maria
Abstract excerpt
Childhood-Onset Schizophrenia (COS) is a very rare and severe psychiatric disorder defined by adult schizophrenia symptoms occurring before the age of 13. We report a microduplication in the 10q26.3 region including part of the Inositol Polyphosphate-5-Phosphatase A (INPP5A) gene that segregates with Schizophrenia Spectrum Disorders (SSDs) in the family of a female patient affected by both COS and Autism Spectrum...
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