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Article

A bacterial toxin that controls cell cycle progression as a deoxyribonuclease I-like protein.

Science (New York, N.Y.) - 13 Oct 2000

Lara-Tejero M, Galán J E

Abstract excerpt

Many bacterial pathogens encode a multisubunit toxin, termed cytolethal distending toxin (CDT), that induces cell cycle arrest, cytoplasm distention, and, eventually, chromatin fragmentation and cell death. In one such pathogen, Campylobacter jejuni, one of the subunits of this toxin, CdtB, was s...

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Identifiers

PMID: 11030657
DOI: 10.1126/science.290.5490.354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11030657-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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