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Article

Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci.

Molecular psychiatry - 1 Feb 2015

Andreassen O A, Harbo H F, Wang Y, Thompson W K, Schork A J, Mattingsdal M, Zuber V, Bettella F, Ripke S, Kelsoe J R, Kendler K S, O'Donovan M C, Sklar P, McEvoy L K, Desikan R S, Lie B A, Djurovic S, Dale A M

Abstract excerpt

Converging evidence implicates immune abnormalities in schizophrenia (SCZ), and recent genome-wide association studies (GWAS) have identified immune-related single-nucleotide polymorphisms (SNPs) associated with SCZ. Using the conditional false discovery rate (FDR) approach, we evaluated pleiotropy in SNPs associated with SCZ (n=21,856) and multiple sclerosis (MS) (n=43,879), an inflammatory, demyelinating...

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Identifiers

PMID: 24468824
DOI: 10.1038/mp.2013.195
PMCID: PMC4356743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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