Article

Genome-wide association studies suggest limited immune gene enrichment in schizophrenia compared to five autoimmune diseases

2015-10-31

Abstract excerpt

There has been intense debate over the immunological basis of schizophrenia, and the potential utility of adjunct immunotherapies. The major histocompatibility complex is consistently the most powerful region of association in genome-wide association studies (GWASs) of schizophrenia, and has been interpreted as strong genetic evidence supporting the immune hypothesis. However, global pathway analyses provide incon...

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Literature Corpus work: 8ffb65be-fdc2-5e2c-adc5-8ca0b5567d33
DOI: 10.1101/030411

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