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Article

Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice.

PloS one - 1 Jan 2014

McDonald Abby A, Kunz Matthew D, McLoon Linda K

Abstract excerpt

Extraocular muscles (EOM) have a strikingly different disease profile than limb skeletal muscles. It has long been known that they are spared in Duchenne (DMD) and other forms of muscular dystrophy. Despite many studies, the cause for this sparing is not understood. We have proposed that differences in myogenic precursor cell properties in EOM maintain normal morphology over the lifetime of individuals with DMD...

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Share to Extremities
Share to Homeobox Protein PITX2
Share to Mice, Inbred mdx

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscular Dystrophy, Animal

Share to Oculomotor Muscles

Share to PAX7 Transcription Factor

Share to Satellite Cells, Skeletal Muscle

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Source

Open in PubMed Open full text

Identifiers

PMID: 24466085
DOI: 10.1371/journal.pone.0086424
PMCID: PMC3897728

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice.PMID 24466085Read ↗

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The sparing of extraocular muscle in dystrophinopathy is lost in mice lacking utrophin and dystrophinSemantic proximity Read ↗

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