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Article

The role of Pitx2 in maintaining the phenotype of myogenic precursor cells in the extraocular muscles.

PloS one - 1 Jan 2013

Hebert Sadie L, Daniel Mark L, McLoon Linda K

Abstract excerpt

Many differences exist between extraocular muscles (EOM) and non-cranial skeletal muscles. One striking difference is the sparing of EOM in various muscular dystrophies compared to non-cranial skeletal muscles. EOM undergo continuous myonuclear remodeling in normal, uninjured adults, and distinct transcription factors are required for the early determination, development, and maintenance of EOM compared to limb...

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Share to Antigens, CD34
Share to Homeobox Protein PITX2
Share to Muscle, Skeletal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscular Dystrophies

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Share to MyoD Protein

Share to PAX7 Transcription Factor

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Source

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Identifiers

PMID: 23505501
DOI: 10.1371/journal.pone.0058405
PMCID: PMC3591328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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