Article
9β Polymorphism of the glucocorticoid receptor gene appears to have limited impact in patients with Addison's disease.
PloS one - 1 Jan 2014
Ross Ian Louis, Dandara Collet, Swart Marelize, Lacerda Miguel, Schatz Desmond, Blom Dirk Jacobus
Abstract excerpt
BACKGROUND: Addison's disease (AD) has been associated with an increased risk of cardiovascular disease. Glucocorticoid receptor polymorphisms that alter glucocorticoid sensitivity may influence metabolic and cardiovascular risk factors in patients with AD. The 9β polymorphism of the glucocorticoid receptor gene is associated with relative glucocorticoid resistance and has been reported to increase the risk of...
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