Article
Binding and uptake of A beta1-42 by primary human astrocytes in vitro.
Glia - 1 Jul 2009
Nielsen Henrietta M, Veerhuis Robert, Holmqvist Bo, Janciauskiene Sabina
Abstract excerpt
Clearance of the amyloid-beta peptide (A beta) as a remedy for Alzheimer's disease (AD) is a major target in on-going clinical trials. In vitro studies confirmed that A beta is taken up by rodent astrocytes, but knowledge on human astrocyte-mediated A beta clearance is sparse. Therefore, by means...
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