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Article

Binding and uptake of A beta1-42 by primary human astrocytes in vitro.

Glia - 1 Jul 2009

Nielsen Henrietta M, Veerhuis Robert, Holmqvist Bo, Janciauskiene Sabina

Abstract excerpt

Clearance of the amyloid-beta peptide (A beta) as a remedy for Alzheimer's disease (AD) is a major target in on-going clinical trials. In vitro studies confirmed that A beta is taken up by rodent astrocytes, but knowledge on human astrocyte-mediated A beta clearance is sparse. Therefore, by means of flow cytometry and confocal laser scanning microscopy (CLSM), we evaluated the binding and internalization of A...

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Identifiers

PMID: 19062178
DOI: 10.1002/glia.20822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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